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All diagnosis and treatment methods were carried out in accordance with existing guidelines ( Definitions CP can be diagnosed when one of the following conditions is established: (1) pancreatic ductal changes (according to the Cambridge classification system, moderate or marked disease), (2) pancreatic calcification appearance, (3) characteristics of CP in endoscopic ultrasound, (4) abnormal results of pancreatic endocrine or exocrine function, or (5) histological proof of CP as described by the Asia-Pacific consensus ( According to the etiologies of CP that we have known, hereditary CP refers to two first-degree relatives or three or more second-degree relatives in two or more generations with recurrent acute pancreatitis and/or CP without any precipitating factors ( To explore the proper cutoff value of smoking consumption to define smoking-related CP, the distribution of cigarette consumption was calculated in the CP patients

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